Data are extensive regarding what needs to be done to help most adults become low risk for CHD. The essentials derive from a basic law of medicine and public health: epidemics are, as set down by Virchow, due to “ . . . disturbances of human culture.”9 The first and foremost of the crucial disturbances producing epidemic rates of major CHD risk factors and CHD is populationwide adverse dietary patterns, along with cigarette smoking and sedentary lifestyle at work and leisure. The diets—high in caloric density, total fat, cholesterol, and saturated and trans fats (from fat- and cholesterol-laden red meats, dairy products, egg yolks, visible fats, and commercial baked goods); high in salt and processed sugars; for some, excessive in alcohol intake; and for all too many, relatively inadequate/low in key micro- and macronutrients from vegetables, fruits, whole grains, and legumes (eg, calcium, iron, magnesium, phosphorus, potassium, antioxidant and other vitamins, fiber, vegetable protein, and mono- and polyunsaturated fats)—account for the epidemic occurrences of adverse levels of serum cholesterol, blood pressure, and other metabolic CHD risk factors.