Author Contributions: Dr Montaner had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Wood, Hogg, Kerr, Montaner.
Acquisition of data: Wood, Hogg, Kerr, Yip.
Analysis and interpretation of data: Wood, Lima, Yip, Marshall.
Drafting of the manuscript: Wood.
Critical revision of the manuscript for important intellectual content: Wood, Hogg, Lima, Kerr, Yip, Marshall, Montaner.
Statistical analysis: Wood, Lima, Yip, Marshall.
Obtained funding: Wood, Hogg, Kerr.
Administrative, technical, or material support: Hogg, Lima, Kerr.
Study supervision: Wood, Montaner.
Financial Disclosures: Dr Hogg reported receiving funding for research and continuing medical education programs from Abbott, Boehringer Ingelheim, and GlaxoSmithKline. Dr Montaner reported receiving educational grants from and serving as an ad hoc advisor to or speaking at various events sponsored by Abbott Laboratories, Agouron Pharmaceuticals Inc, Boehringer Ingelheim Pharmaceuticals Inc, Borean Pharma AS, Bristol-Myers Squibb, DuPont Pharma, Gilead Sciences, GlaxoSmithKline, Hoffmann-La Roche, Immune Response Corporation, Incyte, Janssen-Ortho Inc, Kucera Pharmaceutical Company, Merck Frosst Laboratories, Pfizer Canada Inc, Sanofi Pasteur, Shire Biochem Inc, Tibotec Pharmaceuticals Ltd, and Trimeris Inc. No other authors reported disclosures.
Funding/Support: Dr Kerr is supported by a Canadian Institutes of Health Research New Investigator Award and a Michael Smith Foundation for Health Research Scholar Award. Dr Dias Lima is supported by the Canadian Institutes of Health Research through a fellowship award.
Role of the Sponsor: The Canadian Institutes of Health Research and the Michael Smith Foundation for Health Research had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Additional Contributions: We thank Kathy Li, MSc, Peter Vann, BA, Deborah Graham, LLB, and Kelly Hsu, BA (British Columbia Centre for Excellence in HIV/AIDS, Vancouver) for their administrative support. No compensation was received directly related to clerical support for this study. We also thank the US National Institute on Drug Abuse.