To the Editor: In their Research Letter, Dr Habayeb and colleagues1 showed that plasma levels of the endocannabinoid anandamide (N-arachidonoyl-ethanolamine) were approximately 3-fold higher in women in a miscarriage group compared with those in a live birth group and thus were associated with the outcome in patients presenting with threatened miscarriage. This observation extends previous findings that in peripheral blood mononuclear cells, low levels of fatty acid amide hydrolase, the enzyme that metabolizes anandamide, were associated with subsequent miscarriage in women with uncomplicated early pregnancies.2 On this basis, the authors suggest that measurement of anandamide levels may have the potential to improve the prediction and counseling of women at risk of miscarriage.
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 1
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.