Author Contributions: Ms Shea and Dr Curtis had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Shea, Curtis, Schulman.
Acquisition of data: Shea.
Analysis and interpretation of data: Shea, Curtis, Hammill, DiMartino, Abernethy, Schulman.
Drafting of the manuscript: Shea.
Critical revision of the manuscript for important intellectual content: Shea, Curtis, Hammill, DiMartino, Abernethy, Schulman.
Statistical analysis: Shea, Curtis, Hammill.
Obtained funding: Schulman.
Administrative, technical, or material support: Shea, DiMartino, Schulman.
Study supervision: Curtis, Schulman.
Financial Disclosures: Dr Curtis reports receiving research and salary support from Allergan Pharmaceuticals, GlaxoSmithKline, Lilly, Medtronic, Novartis, Ortho Biotech, OSI Eyetech, Pfizer, and Sanofi-Aventis. Dr Curtis has made available online a detailed listing of financial disclosures (http://www.dcri.duke.edu/research/coi.jsp). Dr Schulman reports receiving research and/or salary support from Actelion, Allergan, Amgen, Arthritis Foundation, Astellas Pharma, Bristol-Myers Squibb, The Duke Endowment, Genentech, Inspire Pharmaceuticals, Johnson & Johnson, Kureha Corporation, LifeMasters Supported SelfCare, Medtronic, Merck, Nabi Biopharmaceuticals, National Patient Advocate Foundation, North Carolina Biotechnology Center, Novartis, OSI Eyetech, Pfizer, Roche, Sanofi-Aventis, Schering-Plough, Scios, Tengion, Theravance, Thomson Healthcare, Vertex Pharmaceuticals, Wyeth, and Yamanouchi USA Foundation; receiving personal income for consulting from Avalere Health, LifeMasters Supported SelfCare, McKinsey & Co, and the National Pharmaceutical Council; having equity in and serving on the board of directors of Cancer Consultants; having equity in and serving on the executive board of Faculty Connection LLC; and having equity in Alnylam Pharmaceuticals. Dr Schulman has made available online a detailed listing of financial disclosures (http://www.dcri.duke.edu/research/coi.jsp). No other disclosures were reported.
Funding/Support: This study was funded by a grant to Duke University from the National Patient Advocate Foundation as manager of the Global Access Project, Washington, DC.
Role of the Sponsor: The National Patient Advocate Foundation had no role in the design and conduct of the study or the collection, analysis, and interpretation of the data. Representatives of the sponsor reviewed a draft of the manuscript. The authors had full control over the preparation of the manuscript and the decision to submit the manuscript for publication.
Previous Presentations: This study was presented in part at a meeting of the Global Access Project, September 20, 2007, Washington, DC; and at the AcademyHealth Annual Research Meeting, June 10, 2008; Washington, DC.
Additional Contributions: We thank Damon M. Seils, MA, Duke University, for editorial assistance and manuscript preparation. Mr Seils did not receive compensation for his assistance apart from his employment at the institution where the study was conducted.