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Incorrect Data Analysis in: Association of Preterm Birth With Long-term Survival, Reproduction, and Next-Generation Preterm Birth FREE

JAMA. 2008;300(2):170-171. doi:10.1001/jama.300.2.170-c.
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Incorrect Data Analysis: In the Original Contribution entitled “Association of Preterm Birth With Long-term Survival, Reproduction, and Next-Generation Preterm Birth” published in the March 26, 2008, issue of JAMA (2008;299[12]:1429-1436), an error occurred in the statistical programming syntax of the analysis of reproduction. A subgroup of individuals who did not survive to age 18 years had been included in the denominator when calculating the proportions who reproduced. Therefore, the reported values for the percentages who reproduced and the associated unadjusted and adjusted relative risks and confidence intervals for the 22- to 27-week and 28- to 32-week gestational age categories were incorrect. The corrected analysis does not alter the statistically significant findings of reduced reproduction among women and men born preterm.

In the Results section of the abstract on page 1429, the eighth sentence should have read as follows: “For men and women born at 22 to 27 weeks, absolute reproduction was 29.3% and 51.9%, with RRs of 0.59 (95% CI, 0.45-0.79) and 0.78 (95% CI, 0.65-0.93), respectively. For 28 to 32 weeks, absolute reproduction was 43.1% and 63.6% for men and women, with RRs of 0.81 (95% CI, 0.77-0.86) and 0.89 (95% CI, 0.86-0.93), respectively.”

In addition, the first sentence of the first paragraph of the section entitled “Educational and Reproductive Outcomes According to Gestational Age at Birth” on page 1431 should have read as follows: “With truncation of the cohort and follow-up through 2004, 282 803 female and 296 517 male survivors remained in the cohort.” The third and fourth sentences of the second paragraph should have read as follows: “With regard to reproduction, only 51.9% of women who had been born at 22 to 27 weeks had subsequently reproduced in contrast to approximately 68% of women born at term. Similar findings were noted for index men, with reproductive rates of 29.3% and 50.4% for men who had been born at 22 to 27 weeks and at term, respectively.”

The corrected Figure 2 and the corrected relevant data from Table 3 appear here.

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Figure 2. Reproduction by Gestational Age at Birth for Women and Men Born in 1967-1976
Graphic Jump Location

Error bars indicate 95% confidence intervals.

Table Graphic Jump LocationTable 3. Educational and Reproductive Outcomes for Index Participants Born in 1967-1976 by Sex and Gestational Age

Figures

Place holder to copy figure label and caption
Figure 2. Reproduction by Gestational Age at Birth for Women and Men Born in 1967-1976
Graphic Jump Location

Error bars indicate 95% confidence intervals.

Tables

Table Graphic Jump LocationTable 3. Educational and Reproductive Outcomes for Index Participants Born in 1967-1976 by Sex and Gestational Age

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