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Letters |

Ventilation Strategies for Acute Lung Injury and Acute Respiratory Distress Syndrome

João Batista Borges, MD; Carlos Roberto Ribeiro Carvalho, MD; Marcelo Britto Passos Amato, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.41-a.
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To the Editor: The studies by Dr Meade and colleagues1 and Dr Mercat and colleagues2 were intended to test a strategy aimed at maximizing alveolar recruitment while limiting hyperinflation. To guarantee applicability at the bedside, both studies made use of fixed targets such as plateau pressures or PEEP/FIO2 ratios with PEEP levels adjusted accordingly. Because PEEP levels were not primarily titrated, the question is how much this approach compromised the test of an “optimum-PEEP” in favor of a “feasible-PEEP.”

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July 2, 2008
Jack J. Haitsma, MD, PhD; Paolo Pelosi, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.39-a.
July 2, 2008
Yuji Oba, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.39-b.
July 2, 2008
Jigeeshu Divatia, MD; Priya Ranganathan, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.40-a.
July 2, 2008
L. M. A. Heunks, MD, PhD; J. G. van der Hoeven, MD, PhD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.40-b.
July 2, 2008
Maureen O. Meade, MD, MSc; Thomas E. Stewart, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.42-a.
July 2, 2008
Luciano Gattinoni, MD, FRCP; Pietro Caironi, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.42-b.
July 2, 2008
Alain Mercat, MD; Jean-Christophe Richard, MD; Laurent Brochard, MD
JAMA. 2008;300(1):39-43. doi:10.1001/jama.300.1.41-b.
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