Author Contributions: Drs Golden and Lazo had full access to all data in the study and take responsibility for the integrity and accuracy of the data analysis.
Study concept and design: Golden, Diez-Roux, Lee, Lyketsos.
Analysis and interpretation of data: Lazo, Carnethon, Bertoni, Schreiner, Diez Roux, Lee, Lyketsos.
Drafting of the manuscript: Golden, Carnethon, Lee.
Critical revision of the manuscript for important intellectual content: Lazo, Bertoni, Schreiner, Diez Roux, Lyketsos.
Statistical analysis: Golden, Lazo, Carnethon, Schreiner, Diez Roux.
Obtaining funding: Diez Roux.
Administrative, technical, or material support: Lee.
Study supervision: Lyketsos.
Financial Disclosures: Dr Golden reports that she serves on the Merck Clinical Diabetes Advisory Board and has received an unrestricted educational grant from Nordisk in the past. Dr Lyketsos reports that he receives grant support from Associated Jewish Federation of Baltimore, the Weinberg Foundation, Forest, GlaxoSmithKline, Eisai, Pfizer, AstraZeneca, Lilly, Ortho-McNeil, Bristol-Myers, and Novartis. He reports that he serves as a consultant/advisor for AstraZeneca, GlaxoSmithKline, Eisai, Novartis, Forest, Supernus, Adlyfe, Takeda, Wyeth, Lundbeck, and Merz. He reports that he has received honorarium or travel support from Pfizer, Forest, GlaxoSmithKline, and Health Monitor. Drs Lazo, Carnethon, Bertoni, Schreiner, Diez Roux, and Lee report no relationships.
Funding/Support: MESA was supported by contracts NO1-HC-95159 through NO1-HC-95165 and NO1-HC-95169 from the National Heart, Lung, and Blood Institute. This research was also supported by grant 5 K23 DK071565, a Patient-Oriented Mentored Scientist Award through the National Institute of Diabetes, Digestive, and Kidney Diseases (Dr Golden) and by grant RO1 HL076831 (Dr Diez Roux, principal investigator).
Role of the Sponsor: The National Heart, Lung, and Blood Institute staff had input into the design and conduct of this study, collection and management of the data, and in review and approval of the manuscript.
Previous Presentations: A portion of this abstract was presented in part as a poster at the 66th Annual Scientific Session of the American Diabetes Association, Chicago, Illinois, June 22-26, 2007.
Additional Contributions: The authors thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org.