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Comment & Response |

Patient-Reported Outcome Alert Monitoring—Reply

Melanie Calvert, PhD1; Heather Draper, PhD2; Derek Kyte, MSc1
[+] Author Affiliations
1Primary Care and Clinical Sciences, University of Birmingham, Birmingham, England
2Medicine, Ethics, Society, and History, University of Birmingham, Birmingham, England
JAMA. 2014;311(4):420-421. doi:10.1001/jama.2013.284330.
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In Reply Dr Thombs and colleagues make 2 overarching points. The first is that a system of active PRO alert monitoring is tantamount to screening, and second, that in the specific case of depression, screening is unlikely to be of benefit and may cause harm.

They conclude that, in line with the principles of the Declaration of Helsinki,1 PRO alert monitoring should only be implemented when the potential benefits outweigh the potential harms and these potential harms are minimized. We agree with this conclusion. The purpose of our Viewpoint was to draw attention to this obligation in the context of PRO alerts and to open debate about how best to achieve this.


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January 22, 2014
Brett D. Thombs, PhD; Carolyn Ells, PhD; Lee Black, JD, LLM
1Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada
2Biomedical Ethics Unit, McGill University, Montreal, Quebec, Canada
3McGill University, Montreal, Quebec, Canada
JAMA. 2014;311(4):420. doi:10.1001/jama.2013.284321.
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