Research Letter |

Association of Mediterranean Diet With Peripheral Artery Disease:  The PREDIMED Randomized Trial

Miguel Ruiz-Canela, PhD1; Ramón Estruch, MD, PhD2; Dolores Corella, DPharm, PhD3; Jordi Salas-Salvadó, MD, PhD4; Miguel A. Martínez-González, MD, PhD1
[+] Author Affiliations
1Department of Preventive Medicine and Public Health, University of Navarra, Pamplona, Spain
2Department of Internal Medicine, Institut d'investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain
3Department of Preventive Medicine, University of Valencia, Valencia, Spain
4Human Nutrition Unit, Sant Joan Hospital, Reus, Spain
JAMA. 2014;311(4):415-417. doi:10.1001/jama.2013.280618.
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The role of nutrition in preventing peripheral artery disease (PAD) remains elusive.1

Mediterranean diets reduce the risk of myocardial infarction and stroke.2,3 They also may reduce the risk of PAD, but this hypothesis has never been tested in a randomized trial. We assessed the association of Mediterranean diets with the occurrence of symptomatic PAD in an exploratory, nonprespecified analysis of a randomized trial.

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Kaplan-Meier Estimates of the Incidence of PAD in the Total Study
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