Cancer of the testicle, the male reproductive organ responsible for making sperm, is common, especially among younger men. In developed nations, the chance of a man developing testicular cancer during his life is 1 in 300. The risk of dying from testicular cancer is very low because it can be treated and even cured when found early. Regular self-examination of the testicles is the best way for a man to detect testicular cancer as early as possible. Treatment and prognosis (chances of cure) depend on the type of cancer found in the testicle. The February 13, 2008, issue of JAMA includes an article about treating advanced testicular cancer.