We're unable to sign you in at this time. Please try again in a few minutes.
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Comment & Response |

Formulation of Treatment Recommendations for Statins—Reply

Paul M Ridker, MD, MPH1; Peter W. F. Wilson, MD2
[+] Author Affiliations
1Center for Cardiovascular Disease Prevention, Brigham and Women’s Hospital, Boston, Massachusetts
2Emory Clinical Cardiovascular Research Institute, Atlanta, Georgia
JAMA. 2014;311(3):306. doi:10.1001/jama.2013.284481.
Text Size: A A A
Published online


In Reply We concur with Dr O’Sullivan and Ms Brown that only those trials that use actual clinical outcomes should inform practice. For the great majority of trials that we cited, the common end point was inclusive of myocardial infarction, stroke, revascularization for unstable angina, or vascular death. How one chooses to weight those outcomes is a matter of opinion, and thus we differ somewhat from O’Sullivan and Brown in that we believe a reduction in the need for angioplasty or bypass surgery is a relevant benefit for patients.


Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

First Page Preview

View Large
First page PDF preview




January 15, 2014
Cait O’Sullivan, PharmD, BScPh, BA; Linda Brown, BScPharm, MSc
1Vancouver Island Health Authority, Campbell River, British Columbia, Canada
JAMA. 2014;311(3):305. doi:10.1001/jama.2013.284440.
January 15, 2014
Mark D. Huffman, MD, MPH; Shah Ebrahim, BM, BS, MSc, DM; Kay Dickersin, PhD
1Northwestern University Feinberg School of Medicine, Chicago, Illinois
2London School of Hygiene and Tropical Medicine, London, England
3Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland
JAMA. 2014;311(3):305-306. doi:10.1001/jama.2013.284443.
Also Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
Please click the checkbox indicating that you have read the full article in order to submit your answers.
Your answers have been saved for later.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.


Some tools below are only available to our subscribers or users with an online account.

0 Citations

Sign in

Purchase Options

• Buy this article
• Subscribe to the journal
• Rent this article ?

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...