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Therapies Aim to Boost “Good” Cholesterol

Mike Mitka
JAMA. 2008;299(5):509-510. doi:10.1001/jama.299.5.509.
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Researchers have yet to develop well-tolerated and accepted therapies for increasing high-density lipoprotein cholesterol (HDL-C), the “good” cholesterol, but that does not mean they are not trying.

Much effort over the past several decades has focused on reducing overall cholesterol levels—an effort that has been fairly successful. A 2005-2006 survey found the average cholesterol level for US adults was under 200 mg/dL for the first time in almost 50 years, according to the US Centers for Disease Control and Prevention. Statin therapy, the mainstay in the cholesterol fight, is credited with reducing coronary artery disease by about 30%.

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Researchers are exploring ways of increasing high-density lipoprotein cholesterol levels to reduce cardiovascular disease risk.



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