Comment & Response |

Combination Pill for Cardiovascular Disease—Reply

Simon Thom, MB,BS, MD1; Anthony Rodgers, MD, PhD2
[+] Author Affiliations
1International Centre for Circulatory Health, Imperial College London, London, England
2George Institute for Global Health, Sydney, Australia
JAMA. 2014;311(1):93-94. doi:10.1001/jama.2013.283146.
Text Size: A A A
Published online


In Reply Drs Tsujimoto and Yamamoto-Honda note that improvements in adherence are of benefit in terms of increasing uptake of proven antiplatelet therapy, but question the importance of the improvements in mean LDL-C level and SBP. In contrast to their suggestion, in high-risk cardiovascular patients there is clear evidence of benefits of blood pressure lowering in patients without hypertension and of more vs less blood pressure lowering13; similarly, there are benefits of LDL-C level lowering in patients without hyperlipidemia and of more vs less LDL-C level lowering.4,5


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




January 1, 2014
Tetsuro Tsujimoto, MD; Ritsuko Yamamoto-Honda, MD, PhD
1Department of Diabetes and Metabolic Medicine, National Center for Global Health and Medicine, Tokyo, Japan
JAMA. 2014;311(1):92-93. doi:10.1001/jama.2013.283130.
January 1, 2014
Michelle Carey, PharmD
1Family Medicine Pharmacy Residency Program, ProMedica Toledo Hospital, Toledo, Ohio
JAMA. 2014;311(1):93. doi:10.1001/jama.2013.283133.
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.

See Also...