Do statins reduce rates of cardiovascular events when used for primary prevention?
When used for primary prevention, statins are associated with lower rates of all-cause mortality, major vascular events, and revascularizations compared with placebo. Statin therapy is not associated with increased rates of life-threatening adverse effects such as cancer.
CVD indicates cardiovascular disease; CHD, coronary heart disease.aAdverse events included cancer, myalgia and rhabdomyolysis, arthritis, and increased liver enzyme.
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