In 1984, the Lipid Research Clinics Program trial provided modest, if controversial, evidence that cholestyramine was associated with a reduction in the risk of coronary heart disease (CHD) in a primary prevention study of men.1 Other evidence for the emergence of a new treatable risk factor came from epidemiological studies, animal studies, and family studies.2 The National Heart, Lung, and Blood Institute (NHLBI) convened the National Cholesterol Education Program (NCEP) to develop recommendations about the detection, evaluation, and treatment of cholesterol in adults. The first Adult Treatment Panel (ATP) used levels of low-density lipoprotein (LDL) cholesterol to define both the thresholds for initiating treatment and the goals or targets of therapy.2
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 5
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
Users' Guides to the Medical Literature
For example, ecologic studies such as the Seven Countries Study16 suggested a strong...
All results at
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.