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Ingredients of Successful Interventions to Improve Medication Adherence

Leah L. Zullig, PhD, MPH1; Eric D. Peterson, MD, MPH2; Hayden B. Bosworth, PhD1,3,4
[+] Author Affiliations
1Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, North Carolina
2Division of Cardiology, Duke University, Durham, North Carolina, and Associate Editor, JAMA
3Division of General Internal Medicine, Department of Medicine, Duke University, Durham, North Carolina
4Department of Psychiatry and Behavioral Sciences and School of Nursing, Duke University, Durham, North Carolina
JAMA. 2013;310(24):2611-2612. doi:10.1001/jama.2013.282818.
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Nonadherence to prescription medication is common and costly.1 On average, 50% of medications for chronic diseases are not taken as prescribed.2 Medication nonadherence is widespread, and accountability for this issue is shared by patients, their caregivers, clinicians, and the health care system as a whole. Furthermore, there is an increasing business case for addressing medication nonadherence; as payment and delivery system models evolve to place health care organizations and clinicians at risk for patient outcomes and downstream costs (eg, bundled payments and accountable care organizations), interest in coordination of care and invention of durable treatments continues to increase.

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