Published Online: November 18, 2013. doi:10.1001/jama.2013.282535.
Study concept and design: Criqui, Denenberg, Allison, Wassel, Ix.
Acquisition of data: Criqui, Carr, Budoff.
Analysis and interpretation of data: Denenberg, Ix, McClelland, Wassel, Rifkin, Carr, Budoff, Allison, Criqui.
Drafting of the manuscript: Criqui.
Critical revision of the manuscript for important intellectual content: Ix, McClelland, Wassel, Rifkin, Carr, Budoff, Allison, Criqui.
Statistical analysis: Denenberg, McClelland, Wassel.
Obtained funding: Carr, Criqui, Budoff.
Administrative, technical, or material support: Carr, Criqui, Denenberg, McClelland, Budoff.
Study supervision: Carr, Budoff, Criqui, McClelland.
Conflict of Interest Disclosures: Dr Criqui reports receipt of a grant to his institution from the National Institutes of Health/National Heart, Lung, and Blood Institute (NIH/NHLBI). Ms Denenberg reports receipt of a grant to her institution from NHLBI. Dr Ix reports receipt of a grant or pending grant from NIH and NHLBI, and support for travel and lectures at scientific conferences from Shire. Dr McClelland reports receipt of a grant to her institution and of support for travel to meetings for the Multi-Ethnic Study of Atherosclerosis (MESA) steering committee from NHLBI/NIH. Dr Rifkin reports receipt of K23 support from a grant from the National Institute of Diabetes and Digestive and Kidney Diseases. Dr Carr reports receipt of a grant to his institution from NIH/NHLBI. Dr Budoff reports receipt of a consulting fee or honorarium from GE. Drs Wassel and Allison report no disclosures. All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest.
Funding/Support: The MESA study was supported by contracts N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, and N01-HC-95169 from the NHLBI.
Role of the Sponsors: The NHLBI participated in the design and conduct of MESA, but did not participate in the analysis or interpretation of the data in the manuscript. Members of the NHLBI staff saw an oral slide presentation of the manuscript presented prior to submission. The NHLBI did not review the manuscript, participate in the decision to submit it, or approve it prior to publication.
Additional Contributions: We thank the other investigators, the staff, and the participants of the MESA study for their valuable contributions. A full list of participating MESA investigators and institutions can be found at http://www.mesa-nhlbi.org. We thank Nova Rogers, BA, for assisting in manuscript preparation. Ms Rogers was not additionally compensated for completion of work associated with this article.
Correction: This article was corrected online December 2, 2014, for incorrect absolute risk values.