Study concept and design: Martin, Blaha, Elshazly, Kwiterovich, Jones.
Acquisition of data: Martin, Blaha, Jones.
Analysis and interpretation of data: Martin, Elshazly, Toth, Blumenthal, Jones.
Drafting of the manuscript: Martin, Blaha, Jones.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Martin, Elshazly, Jones.
Administrative, technical, or material support: Blaha, Toth, Kwiterovich, Jones.
Study supervision: Blaha, Jones.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Blaha reports pending grant funding from the National Institutes of Health and the US Food and Drug Administration and participating in a roundtable discussion with Regeneron. Dr Toth reports consulting for Amgen, AstraZeneca, Atherotech, Boehringer-Ingelheim, GlaxoSmithKline, Kowa, Liposcience, and Merck; serving on the speakers bureau for Amarin, Amgen, AstraZeneca, Genzyme, Kowa, Merck; and receiving travel accommodations from Atherotech. Dr Kwiterovich reports receiving compensation for consultancy from Merck and research grants from Pfizer, Amarin, and Merck. Dr Jones reports serving on the medical advisory board for, and receiving grant funding from, Atherotech. Drs Martin and Jones are listed on a planned provisional patent related to the novel method. No other disclosures were reported.
Funding/Support:Atherotech participated in the collection of data by providing the investigators with deidentified data generated from commercial lipid analyses. Dr Martin is supported by the Pollin Cardiovascular Prevention Fellowship, as well as the Marie-Josée and Henry R. Kravis endowed fellowship. Dr Blumenthal is supported by the Kenneth Jay Pollin Professorship in Cardiology.
Role of the Sponsor: Atherotech had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.