Iron deficiency, with its consequent effects on anemia, immune function, cognitive development, and physical capacity, is estimated to be one of the most prevalent nutritional problems worldwide.1 Yet iron is the second most abundant element on the earth’s crust. How can this be? The answer is an intriguing one that has important implications for the understanding of iron biology and may point toward safer ways of administering iron. In brief, the useful oxidoreductive characteristics of iron have made it the element of choice in many biochemical pathways for both the human host and its legions of pathogens, leading to a highly evolved metabolic competition for this element.2
Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more
Subscribe for full-text access to content from 1998 forward and a host of useful features
Activate your current subscription (AMA members and current subscribers)
Purchase Online Access to this article for 24 hours
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Web of Science® Times Cited: 1
Customize your page view by dragging & repositioning the boxes below.
More Listings atJAMACareerCenter.com >
and access these and other features:
Enter your username and email address. We'll send you a link to reset your password.
Enter your username and email address. We'll send instructions on how to reset your password to the email address we have on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.