0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Medical News & Perspectives |

Early Treatment of Ischemic Stroke With Intravenous tPA Reduces Disability Risk

Mike Mitka, MSJ
JAMA. 2013;310(11):1111. doi:10.1001/jama.2013.278292.
Text Size: A A A
Published online

Extract

Very early treatment with intravenous thrombolysis for patients with mild-to-moderate acute ischemic strokes was associated with decreased risk of having permanent disability, according to a European study published August 22 in Stroke.

The American Heart Association/American Stroke Association (AHA/ASA) recommends getting patients to a hospital as soon as possible after onset of acute ischemic stroke symptoms for treatment with intravenous tissue-type plasminogen activator (tPA). This thrombolytic agent allows reperfusion of the brain and has proven benefit for select patients. AHA/ASA guidelines recommend giving tPA to treat stroke up to 4.5 hours after onset of symptoms. But sooner is far better than later because stroke rapidly causes irreversibly injured tissue, with 2 million additional neurons lost each minute until reperfusion is achieved.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Articles Related By Topic
Related Collections
Jobs
JAMAevidence.com

Users' Guides to the Medical Literature
Table 9.2-3 Refuted Evidence From Observational Studiesa

The Rational Clinical Examination
Quick Reference

brightcove.createExperiences();