Study concept and design: Chiang, You, Chen.
Acquisition of data: Chiang, Yang, You, Lai, Chen.
Analysis and interpretation of data: Chiang, Yang, You, Chen.
Drafting of the manuscript: Chiang, You.
Critical revision of the manuscript for important intellectual content: Chiang, Yang, You, Lai, Chen.
Statistical analysis: Chiang, Yang, You.
Administrative, technical, or material support: Chiang, You.
Study supervision: Lai, Chen.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Chen reported serving as a consultant to Bristol-Myers Squibb, Merck Sharp & Dohme, GlaxoSmithKline, and Roche; receiving grants from Bristol-Myers Squibb and Roche; and receiving payment for lectures from Bristol-Myers Squibb, Merck Sharp & Dohme, and Roche. No other disclosures were reported.
Funding/Support: This work was supported by grants from the Bureau of Health Promotion, Department of Health, Executive Yuan, Taiwan, and Academia Sinica.
Role of the Sponsor: The Bureau of Health Promotion, Department of Health, Executive Yuan, Taiwan, and Academia Sinica had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.