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Comment & Response |

Efficacy of Sublingual Immunotherapy

Franco Frati, MD1; Cristoforo Incorvaia, MD2; Giovanni Passalacqua, MD3
[+] Author Affiliations
1Department of Medical and Surgical Specialty and Public Health, University of Perugia, Perugia, Italy
2Allergy and Pulmonary Rehabilitation Unit, ICP Hospital, Milan, Italy
3Allergy and Respiratory Diseases, University of Genoa, Genoa, Italy
JAMA. 2013;310(6):643-644. doi:10.1001/jama.2013.7646.
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To the Editor The primary objective of the systematic review by Dr Lin and colleagues1 was “to review the clinical efficacy and safety of sublingual immunotherapy delivered as an aqueous solution as can potentially be done in the United States.” The authors reported that there are physicians in the United States who use subcutaneous aqueous allergens off-label for sublingual desensitization. However, the doses administered by subcutaneous immunotherapy and sublingual immunotherapy are very different.

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August 14, 2013
Sandra Y. Lin, MD; Catalina Suarez-Cuervo, MD; Jodi Segal, MD, MPH
1Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, Baltimore, Maryland
2Department of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland
JAMA. 2013;310(6):644-645. doi:10.1001/jama.2013.7652.
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