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Comment and Response |

Smoking Cessation, Weight Change, and Risk of Cardiovascular Disease—Reply

Carole Clair, MD, MSc1; Nancy A. Rigotti, MD2; James B. Meigs, MD, MPH3
[+] Author Affiliations
1Department of Ambulatory Care and Community Medicine, Lausanne University, Lausanne, Switzerland
2Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston
3General Medicine Division, Massachusetts General Hospital, Boston
JAMA. 2013;310(3):323. doi:10.1001/jama.2013.7945.
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In Reply Dr Ji and colleagues suggest that other changes in behavior associated with smoking cessation, such as change in diet and decrease in alcohol consumption, might contribute to the decrease in cardiovascular disease we observed in our study. We agree that smokers might adopt a healthier lifestyle when they quit smoking.

In the Comment section of our article, we cited this as one of the mechanisms for a decrease in cardiovascular disease associated with smoking cessation. However, the main objective of our study was not to explore potential mechanisms responsible for the decrease in cardiovascular risk when smokers quit smoking but to test the hypothesis that weight gain following smoking cessation does not attenuate the cardiovascular benefits of smoking cessation.


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July 17, 2013
Yuanyuan Ji, MD, PhD; Zhidong Wang, MD, PhD; Zongfang Li, MD, PhD
1Scientific Research Center, Xi’an Jiaotong University, Xi’an, China
2Department of General Surgery, Xi’an Jiaotong University, Xi’an, China
JAMA. 2013;310(3):322. doi:10.1001/jama.2013.7939.
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