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Comment and Response |

Smoking Cessation, Weight Change, and Risk of Cardiovascular Disease

Yuanyuan Ji, MD, PhD1; Zhidong Wang, MD, PhD2; Zongfang Li, MD, PhD2
[+] Author Affiliations
1Scientific Research Center, Xi’an Jiaotong University, Xi’an, China
2Department of General Surgery, Xi’an Jiaotong University, Xi’an, China
JAMA. 2013;310(3):322. doi:10.1001/jama.2013.7939.
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To the Editor Dr Clair and colleagues1 reported the results from a prospective, community-based cohort study using data from the Framingham Offspring Study collected from 1984 through 2011. The results demonstrated that smoking cessation was associated with a lower risk of cardiovascular disease events among participants without diabetes, and that the weight gain that occurred following smoking cessation did not modify this association.1 Although we agree that this supports a net cardiovascular benefit of smoking cessation, we have several concerns with respect to this study.


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July 17, 2013
Carole Clair, MD, MSc; Nancy A. Rigotti, MD; James B. Meigs, MD, MPH
1Department of Ambulatory Care and Community Medicine, Lausanne University, Lausanne, Switzerland
2Tobacco Research and Treatment Center, Massachusetts General Hospital, Boston
3General Medicine Division, Massachusetts General Hospital, Boston
JAMA. 2013;310(3):323. doi:10.1001/jama.2013.7945.
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