Study concept and design: Ko, Tu, Samadashvili, Hannan.
Acquisition of data: Samadashvili, Hannan.
Analysis and interpretation of data: All authors.
Drafting of the manuscript: Ko.
Critical revision of the manuscript for important intellectual content: All
Statistical analysis: Samadashvili, Guo.
Obtained funding: Tu, Ko.
Administrative, technical, or material support: Hannan.
Study supervision: Tu, Hannan.
Conflict of Interest Disclosures: All authors
have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and
none were reported.
Funding/Support: This study was supported by
the Institute for Clinical Evaluative Sciences (ICES),
which is funded by an annual grant from the Ontario Ministry of Health and
Long-term Care (MOHLTC). The authors acknowledge that the clinical registry data
used in this publication are from the Cardiac Care Network of
Ontario and its member hospitals. The Cardiac Care Network of Ontario serves as a
system support to the MOHLTC, Local Health Integration Networks, and service providers and is
dedicated to improving the quality, efficiency, access and equity in the delivery of the continuum
of adult cardiovascular services in Ontario, Canada. The Cardiac Care Network of Ontario is funded
by the MOHLTC. The analysis of this study was supported by a Canadian
Institutes of Health Research (CIHR) operating grant MOP (102487). Dr Ko is
supported by a CIHR New Investigator Award. Dr Tu is supported by a Canada Research Chair in Health
Services Research and a Career Investigator Award from the Heart and
Stroke Foundation of Ontario. Dr Austin is supported by a Career Investigator Award
from the Heart and Stroke Foundation of Ontario.
Role of the Sponsor: The sponsors had no role in the design and conduct of the
study; collection, management, analysis, and interpretation of the data; preparation, review, or
approval of the manuscript; or decision to submit this manuscript.
Disclaimer: No endorsement by any of the supporting organizations is intended or
should be inferred.