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Comment and Response |

Myocardial Thinning in Patients With Coronary Artery Disease—Reply

Dipan J. Shah, MD1; Han W. Kim, MD2; Raymond J. Kim, MD2
[+] Author Affiliations
1Methodist DeBakey Heart and Vascular Center, Houston, Texas
2Duke Cardiovascular Magnetic Resonance Center, Duke University Medical Center, Durham, North Carolina
JAMA. 2013;310(2):207-208. doi:10.1001/jama.2013.7936.
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In Reply We agree that following an acute MI, infarct healing and wall thinning may not be completed for weeks to months. In our population, patients with an acute MI within 2 weeks of potential enrollment were excluded, and 71% of enrolled patients had a history of prior MI.

We do not have data concerning the time between the diagnosis of MI and the performance of delayed-enhancement CMR imaging. However, if our population had included a sizable fraction of patients with relatively recent MI, the reported prevalence of 19% with regional wall thinning may represent an underestimate compared with a population in which all patients with an MI within the last 6 months were excluded.

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July 10, 2013
Neng Dai, MD; Da-Chun Xu, MD, PhD; Ya-Wei Xu, MD, PhD
1Tenth People’s Hospital of Tongji University, Shanghai, China
JAMA. 2013;310(2):207. doi:10.1001/jama.2013.7921.
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