Study concept and design: Liu, Guralnik, Spring, Rejeski, McDermott.
Acquisition of data: Domanchuk, Ferrucci, Lloyd-Jones, McDermott.
Analysis and interpretation of data: Liu, Guralnik, Criqui, Spring, Tian, Ferrucci, Lloyd-Jones, Kibbe, Tao, Zhao, Liao, McDermott.
Drafting of the manuscript: Rejeski, McDermott.
Critical revision of the manuscript for important intellectual content: Liu, Guralnik, Criqui, Spring, Tian, Domanchuk, Ferrucci, Lloyd-Jones, Kibbe, Tao, Zhao, Liao, Rejeski, McDermott.
Statistical analysis: Liu, Guralnik, Spring, Tian, Kibbe, Tao, Liao, McDermott.
Obtained funding: Guralnik, Criqui, Rejeski, McDermott.
Administrative, technical, or material support: Domanchuk, Kibbe, McDermott.
Study supervision: Spring, Domanchuk, Ferrucci, Zhao, Rejeski, McDermott.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr McDermott reports being a medical editor for the Foundation for Informed Medical Decision Making, consulting for Ironwood Pharmaceuticals, and receipt of travel expenses from the American Heart Association as an SACC member. Dr Spring reports board membership with Actigraph. No other disclosures were reported.
Funding/Support: Supported by R01-HL088589 and RO1-HL107510 from the National Heart, Lung, and Blood Institute. Supported in part by the Intramural Research Program, National Institutes on Aging (NIA), National Institutes of Health. No other funding was used to carry out the study or complete the manuscript.
Role of the Sponsor: The funding agencies played no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; preparation of the manuscript; and decision to submit the manuscript for publication.
Disclaimer: Dr McDermott, an Associate Editor for JAMA, was not involved in the evaluation of or decision to publish this article.