Author Contributions: Drs Gantz and Warren had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Nygaard, Brubaker, Zyczynski, Cundiff, Richter, Fine, Visco.
Acquisition of data: Nygaard, Brubaker, Zyczynski, Cundiff, Menefee, Visco, Meikle.
Analysis and interpretation of data: Nygaard, Brubaker, Zyczynski, Cundiff, Richter, Gantz, Fine, Menefee, Ridgeway, Warren, Zhang, Meikle.
Drafting of the manuscript: Nygaard, Brubaker, Zyczynski, Cundiff, Richter, Fine, Menefee, Ridgeway, Zhang, Meikle.
Critical revision of the manuscript for important intellectual content: Nygaard, Brubaker, Zyczynski, Cundiff, Richter, Gantz, Fine, Menefee, Visco, Warren, Meikle.
Statistical analysis: Richter, Gantz, Fine, Warren, Zhang, Meikle.
Obtained funding: Nygaard, Brubaker, Zyczynski, Cundiff, Meikle.
Administrative, technical, or material support: Zyczynski.
Study supervision: Nygaard, Richter, Gantz, Fine, Menefee, Meikle.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Zyczynski reported serving as a consultant to Johnson & Johnson and Key Tech. Dr Richter reported receiving research grants from Pelvalon, Astellas, University of Califonia/Pfizer, Pfizer, and Warner Chilcott; and serving as a consultant to Astellas (advisory board), GlaxoSmithKline, Uromedica, IDEO, Pfizer, and Xanodyne. Dr Visco reported serving as a consultant to Intuitive Surgical. No other disclosures were reported.
Funding/Support: This research was supported by grants U01 HD41249, U10 HD41250, U10 HD41261, U10 HD41267, U10 HD54136, U10 HD54214, U10 HD54215, U10 HD54241, U10 HD054136, U10 HD054215, U10 HD041261, U10 HD041267, U10 HD069006, U10 HD054214, U10 HD041250, and U01 HD069031 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, and the Office of Research on Women's Health at the National Institutes of Health.
Role of the Sponsors: The Eunice Kennedy Shriver National Institute of Child Health and Human Development (Dr Meikle) played a role in the design and conduct of the study; the collection, analysis, and interpretation of the data; and in the preparation, review, and approval of the manuscript.
Pelvic Floor Disorders Network Members: In addition to the authors, the following members of the Pelvic Floor Disorders Network participated in the Extended CARE trial: University of Alabama at Birmingham: K. Burgio, P. Goode, R. Varner, V. Willis; University of Iowa, Iowa City: D. Brandt, D. Haury, K. Kreder, C. Bradley; Johns Hopkins Medical Institutes, Baltimore, Maryland: V. Handa, M. Sauter; Loyola University, Chicago, Illinois: M. FitzGerald, K. Kenton, D. Koch, C. Ball; University of Michigan, Ann Arbor: J. Wei, J. DeLancey, N. Janz, D. Smith, P. Wren, J. Imus, B. Marchant, Y. Casher, M. Brown, C. Spino; University of North Carolina at Chapel Hill: A. Connolly, M. Jannelli, M. Loomis, A. Murphy, E. Wells, W. Whitehead; University of Pittsburgh/Magee-Women's Hospitals, Pittsburgh, Pennsylvania: D. Borello-France, J. Gruss, W. Leng, P. Moalli, C. Ghetti; previously NIH: A. Weber; PFDN Steering Committee Chair: K. Hartman.
Online-Only Material: The Author Audio Interview is available here.
Additional Contributions: We gratefully acknowledge the expertise and assistance of Barry Eggleston, MS, from RTI International, in creating the survival models used in the analyses. Mr Eggleston received compensation for his contribution.
This article was corrected for errors on May 21, 2013 and August 22, 2013.