Author Contributions: Drs Rodd and Weiler, the senior authors of this article, had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Sharma, Jones, L’Abbé, Khamessan, Rodd, Weiler.
Acquisition of data: Gallo, Comeau, Vanstone, Agellon, Jones, Weiler.
Analysis and interpretation of data: Gallo, Sharma, Jones, L’Abbé, Rodd, Weiler.
Drafting of the manuscript: Gallo, Vanstone, Rodd, Weiler.
Critical revision of the manuscript for important intellectual content: All authors.
Statistical analysis: Gallo, Sharma, Rodd, Weiler.
Obtained funding: Jones, Rodd, Weiler.
Administrative, technical, or material support: Gallo, Comeau, Vanstone, Agellon, Jones, Khamessan, Rodd, Weiler.
Study supervision: Gallo, Vanstone, Agellon, L’Abbé, Rodd, Weiler.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Ms Gallo reports travel support from CIHR Human Development Child and Youth Health and the American Society for Bone and Mineral Research. Dr Sharma reports consulting fees for analyses prepared for Drs Weiler and Rodd. Dr Jones reports that he is cofounder and scientific advisory board member for Cytochroma Inc and has received payment for speakers bureaus from Genzyme/Sanofi. No other disclosures were reported.
Funding/Support: This work was supported by funding from the Canadian Institutes for Health Research, Nutricia Research Foundation, and the Canadian Foundation for Innovation and in-kind support from Europharm International Canada Inc for provision of the supplements. Fonds de la Recherche en Santé du Québec provided personal funding for the doctoral student (Ms Gallo) and the Canada Research Chairs provided a salary award to Dr Weiler.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.
Previous Presentations: This work was presented at the Experimental Biology meeting on April 21, 2012; at the Canadian Nutrition Society meeting on May 25, 2012; at the Canadian Paediatric Society conference on June 8, 2012; and at the British Columbia Children's Hospital and Montreal Children's Hospital Grand Rounds on March 23, 2012, and May 2, 2012, respectively.
Online-Only Material: The Author Audio Interview is available here.
Additional Contributions: We thank John Mitchell, MD, FRCPC, Montreal Children's Hospital, for his unpaid role as safety officer, the Montreal Children's Hospital clinical laboratory for mineral analyses, and all of the pediatricians as well as Lakeshore General Hospital maternity ward for help with recruitment. We thank McGill University graduate students Samira Bou Raad, MSc, Saja Al Saleh, MSc, Sonia Jean-Philippe, RD, MSc, and Anna Phan, RD, MSc, for help with study measurements. Mss Jean-Philippe and Phan received financial remuneration for their assistance in dietary assessment. Finally, we thank all of the families who agreed to participate in this study and the Mary Emily Clinical Nutrition Research Unit of the School of Dietetics and Human Nutrition.