Author Contributions: Dr Titomanlio had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Romanello, Alberti, Titomanlio.
Acquisition of data: Romanello, Spiri, Marcuzzi, Zanin, Riviere, Vizeneux, Moretti, Carbajal.
Analysis and interpretation of data: Romanello, Zanin, Boizeau, Mercier, Wood, Zuccotti, Crichiutti, Alberti, Titomanlio.
Drafting of the manuscript: Romanello, Zanin, Titomanlio.
Critical revision of the manuscript for important intellectual content: Romanello, Spiri, Marcuzzi, Zanin, Boizeau, Riviere, Vizeneux, Moretti, Carbajal, Mercier, Wood, Zuccotti, Crichiutti, Alberti, Titomanlio.
Statistical analysis: Boizeau, Riviere, Alberti.
Administrative, technical, or material support: Marcuzzi, Moretti, Carbajal.
Study supervision: Romanello, Spiri, Zanin, Vizeneux, Mercier, Wood, Zuccotti, Crichiutti, Titomanlio.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: No funding organization(s) or sponsor(s) had a role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Additional Contributions: We thank all the families and physicians who participated in our study. We thank Rym Boulkedid, MSc, and Damir Mohamed, MSc, Clinical Research Unit of the INSERM-CIE5, Paris, France, for their help with statistical analysis. Neither individual received compensation for work on this article.