By 2007, in addition to six countries with existing national blood policies, such policies were established in six additional countries and were in development in one country. In 2010, 12 countries continued to report the presence of a national blood policy, including one country that was revising its existing policy. Since the most recent reporting in 2007, a legislative framework supporting the national blood policy had been enacted in two additional countries.# By 2010, 11 countries had increased total whole blood unit collections relative to 2007, and national blood services in all countries reported increased collections relative to 2003.** South Africa had already achieved 17.4 whole blood units collected per 1,000 population per year in 2003, and Botswana reached 11 units per 1,000 population in 2005. In both countries, whole blood collections continued to be >10 units per 1,000 population per year through 2010. In 2009, collections by the national blood service in Guyana (10.2 units per 1,000 population) had crossed this threshold, with Namibia (9.7 units per 1,000 population) close to this threshold. Six other countries had increased collection rates per 1,000 population since 2007. In 2010, 11 of the 14 PEPFAR-supported countries continued to have either 100% of collections by national blood services from voluntary non-remunerated donors or an increase in the percentage of collections from these persons in comparison with 2007, including Haiti, despite structural losses from the 2010 earthquake. Since 2007, the national blood services in 12 countries have reported an overall decrease in the percentage of collected blood units reactive for HIV, despite persistently high HIV population prevalence as estimated by the United Nations.