Author Contributions: Drs Altenburg and Boersma had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Altenburg, de Graaff, Sloos, van der Werf, Boersma.
Acquisition of data: Altenburg, van Haren, Koppers, van der Werf.
Analysis and interpretation of data: Altenburg, de Graaff, Stienstra, van der Werf, Boersma.
Drafting of the manuscript: Altenburg, Stienstra, Sloos, van der Werf.
Critical revision of the manuscript for important intellectual content: Altenburg, de Graaff, Stienstra, van Haren, Koppers, van der Werf, Boersma.
Statistical analysis: Altenburg, Stienstra, Boersma.
Obtained funding: Boersma.
Administrative, technical, or material support: Boersma.
Study supervision: de Graaff, van der Werf, Boersma.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Boersma reported serving on an advisory board for, and receiving payment for an educational presentation from, Pfizer. No other authors reported disclosures.
Funding/Support:Dr Altenberg and Dr Boersma are supported by a research grant from the Foreest Medical School, an independent scientific institution based in the Alkmaar Medical Centre. This grant was used for paying salaries for the main researcher and research assistant, to provide logistical support, and for laboratory tests, pulmonary function testing, and imaging. This study was supported by an unrestricted research grant from GlaxoSmithKline. Teva Netherlands supplied the azithromycin tablets used in the study. No salaries or stipends were paid.
Role of the Sponsors: The funders had no role in the design and conduct of the study; the collection, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript.
Additional Contributions: We thank Tineke Tossijn-Groot and Piet Singer and the rest of the staff of the Department of Medical Microbiology, Medical Center Alkmaar, Alkmaar, the Netherlands, for processing sputum samples and providing advice; Irma Schoe (Department of Pulmonary Diseases, Medical Center Alkmaar) for assistance with follow-up visits; Margreet Schoorl and Marianne Schoorl (Department of Clinical Chemistry, Haematology & Immunology, Medical Center Alkmaar) for their help with processing and storing of blood samples; and Tjeerd van der Ploeg, MSc (Medical Center Alkmaar/Inholland University, Alkmaar), for statistical help and advice. We also thank all pulmonary physicians and the outpatient department staff of the participating hospitals: J. M. W. van Haarst, MD, PhD, and P. J. H. Janssen, MD (Tergooi Hospitals, Hilversum), I. van der Lee, MD, PhD (Spaarne Hospital, Hoofddorp), F. Brijker, MD, PhD (Diakonessen Hospital, Utrecht), B. Hajian, MD, PhD (Amsterdam Medical Centre, Amsterdam, the Netherlands), J. W. K. van den Berg, MD, PhD (Isala Clinics, Zwolle), W. J. A. Wijnands, MD, PhD (Deventer Hospital, Deventer), B. T. J. van den Berg, MD, PhD (St Lucas Andreas Hospital, Amsterdam), M. H. E. Reijers, MD, PhD (University Lung Centre Dekkerswald, Groesbeek), M. M. van der Eerden, MD, PhD (Erasmus Medical Centre, Rotterdam), and E. F. G. Kapteijns, MD (Rode Kruis Hospital, Beverwijk). These collaborators did not receive any compensation for their contributions.