The evolving capacity to noninvasively image the contracting heart and assess structure, function, perfusion, and viability has led to remarkable progress in the ability to more accurately make cardiovascular diagnoses and to augment prognostic capabilities.1 For the cardiovascular specialist, when guided by patients' history and physical examination results, the transthoracic echocardiogram has earned its respected front-line role for evaluation of cardiac structure and function. Whether additional imaging is needed and by which modality is highly dependent on the specific clinical circumstance. In this issue of JAMA, 2 articles2,3 describe studies using cardiac magnetic resonance (CMR) imaging with the objective of determining whether incremental clinical insights can be obtained from the location and extent of fibrosis as assessed by late gadolinium enhancement (LGE).
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