Author Contributions: Dr Ahimastos had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Ahimastos, Blombery, Kingwell.
Acquisition of data: Ahimastos, Walker, Askew, Leicht, Pappas, Golledge.
Analysis and interpretation of data: Ahimastos, Walker, Askew, Blombery, Reid, Golledge, Kingwell.
Drafting of the manuscript: Ahimastos, Reid, Kingwell.
Critical revision of the manuscript for important intellectual content: Ahimastos, Walker, Askew, Leicht, Pappas, Blombery, Reid, Golledge, Kingwell.
Statistical analysis: Ahimastos, Reid, Kingwell.
Obtained funding: Ahimastos, Kingwell.
Administrative, technical, or material support: Walker, Askew, Leicht, Pappas.
Study supervision: Ahimastos, Walker, Askew, Blombery, Golledge, Kingwell.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Blombery reported serving as a board member for, and receiving payment for lectures from, sanofi-aventis. Dr Golledge reported receiving grants or grants pending from the government of Queensland, the National Health and Medical Research Council of Australia, the National Heart Foundation of Australia, the BUPA Foundation, and Novartis; and receiving travel expenses to speak at national and international meetings. No other authors reported disclosures.
Funding/Support: This study was supported by the National Heart Foundation of Australia, the National Health and Medical Research Council of Australia, and the Operational Infrastructure Support Program of the Victorian State Government, Australia (Dr Ahimastos and Dr Kingwell).
Role of the Sponsor: The funding agencies had no role in the design and conduct of the study; the collection, management, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript. Ramipril used in the study was purchased by the investigators.
Online-Only Material: The Author Audio Interview is available here.