Published Online: January 22, 2013. doi:10.1001/jama.2013.159
Author Contributions: Dr Jubran had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Jubran, Duffner, Collins, Lanuza, Hoffman, Tobin.
Acquisition of data: Jubran, Duffner.
Analysis and interpretation of data: Jubran, Grant, Duffner, Collins, Hoffman, Tobin.
Drafting of the manuscript: Jubran, Hoffman, Tobin.
Critical revision of the manuscript for important intellectual content: Jubran, Grant, Tobin.
Statistical analysis: Jubran, Grant, Tobin.
Obtained funding: Jubran, Collins, Hoffman, Tobin.
Administrative, technical, or material support: Jubran, Duffner.
Study supervision: Jubran, Duffner, Collins.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Tobin declares receipt of royalties from McGraw-Hill for 2 books published on critical care medicine. The other authors report no disclosures.
Funding/Support: This work was supported by funding from the National Institute of Nursing Research (RO1 NR008782).
Role of the Sponsor: The National Institute of Nursing Research had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; or preparation, review, or approval of the manuscript.
Additional Contributions: The authors gratefully thank the Pulmonary and Critical Care Medicine fellows of Loyola University Stritch School of Medicine and the medical staff at RML Hospital for their assistance with recruitment; respiratory therapists at RML Hospital for their assistance with implementing the weaning methods; Jay Shannon, MD, University of Texas Southwestern Medical School, Dallas; and the institutional review board at RML Hospital, which served on the data and safety monitoring board. None received compensation beyond their normal salaries.