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Energy Drinks and Caffeine-Related Adverse Effects

Kent A. Sepkowitz, MD
JAMA. 2013;309(3):243-244. doi:10.1001/jama.2012.173526.
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In 1911, under authority granted by the recently enacted Food and Drug Act, US agents seized 40 kegs and 20 barrels of Coca-Cola syrup in Chattanooga, Tennessee.1,2 The group, led by chief chemist Harvey Wiley, considered the caffeine in Coca-Cola to be a significant public health hazard (both cocaine and alcohol had been removed from the recipe in the previous decade). The case continued for years. Eventually Coca-Cola decreased the caffeine content in this product and legal action was dropped.3

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