Author Contributions: Dr Kaddis had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Campbell-Thompson, Atkinson, Kaddis.
Acquisition of data: Campbell-Thompson, Wasserfall, Montgomery, Kaddis.
Analysis and interpretation of data: Campbell-Thompson, Atkinson, Kaddis.
Drafting of the manuscript: Atkinson, Kaddis.
Critical revision of the manuscript for important intellectual content: Campbell-Thompson, Wasserfall, Montgomery, Atkinson, Kaddis.
Statistical analysis: Kaddis.
Obtained funding: Campbell-Thompson, Atkinson.
Administrative, technical, or material support: Campbell-Thompson, Wasserfall, Montgomery, Atkinson.
Study supervision: Campbell-Thompson, Wasserfall, Atkinson.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest and none were reported.
Funding/Support: This research was performed with the support of the Network For Pancreatic Organ Donors with Diabetes program, a collaborative type 1 diabetes research project sponsored by the Juvenile Diabetes Research Foundation International, that provides tissues to approved investigators for the purposes of advancing the understanding of mechanisms that lead to type 1 diabetes (grant 6-2006-1140 to Dr Campbell-Thompson; and grant 25-2007-874 to Dr Atkinson, with a subcontract to Dr Kaddis). Organ procurement organizations partnering with the program to provide donor organ and tissue samples are listed at http://www.jdrfnpod.org/our-partners.php.
Role of the Sponsor: The funding organizations had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Disclaimer: The interpretation and reporting of organ donor data are the responsibilities of the authors and in no way should be seen as an official policy of or interpretation by the Organ Procurements and Transplantation Network or the US government.
Additional Contributions: Organ donor information was supplied by the United Network of Organ Sharing as the contractor for the Organ Procurements and Transplantation Network, or obtained from medical charts. Desmond Schatz, MD (University of Florida), and Alberto Pugliese, MD (University of Miami), critically reviewed medical charts, the manuscript, and participated in discussions about data analysis. Patrick A. Rowe, PhD (University of Florida), provided interpretation of the data. David Smith, PhD (City of Hope), provided assistance with constructing general linear models. No individuals received compensation for their contributions to this work.