Prescription drugs, including amphetamines, opioids, and benzodiazepines, provide therapeutic value to millions of Americans. At the same time, there are increasing concerns about the skyrocketing rates of prescription abuse and overdose deaths. The annual number of fatal drug overdoses in the United States now surpasses the annual number of motor vehicle deaths, and overdose deaths attributable to prescription opioids—nearly 15 000 in 2008—exceed those attributable to cocaine and heroin combined.1
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