Author Contributions: Dr Holmquist had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Holmqvist, Neovius, Askling.
Acquisition of data: Holmqvist, Neovius, Eriksson, Askling.
Analysis and interpretation of data: Holmqvist, Neovius, Eriksson, Mantel, Wållberg-Jonsson, Jacobsson, Askling.
Drafting of the manuscript: Holmqvist, Askling.
Critical revision of the manuscript for important intellectual content: Holmqvist, Neovius, Eriksson, Mantel, Wållberg-Jonsson, Jacobsson, Askling.
Statistical analysis: Holmqvist, Neovius, Eriksson, Askling.
Obtained funding: Askling.
Administrative, technical, or material support: Holmqvist, Askling.
Study supervision: Holmqvist, Neovius, Askling.
Conflict of Interest Disclosures: All authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Neovius reported participating in advisory boards for Pfizer (rheumatology) and Abbott (nonrheumatology) (unrelated to the current work); participating in research projects fully or partly funded by Schering-Plough, AstraZeneca, Novo Nordisk, Pfizer, and Roche (unrelated to the current work); and serving as a consultant (unrelated to rheumatology since 2008) to Pfizer, sanofi-aventis, and Abbott. Dr Wållberg-Jonsson reported serving as an invited speaker at a seminar organized by Roche (unrelated to the current work); contributing to patient information days organized by the Swedish Rheumatism Association (unrelated to the current work); receiving royalties for writing book chapters meant for education in rheumatology and cardiology; and receiving funding from Roche to travel to a conference in 2012. Dr Askling reported receiving grants within a public-private research consortium partly financed by Pfizer and AstraZeneca (unrelated to the current work); serving as an invited speaker at meeting organized by Merck on an unrelated topic; and serving as a member of a safety advisory committee at AstraZeneca.
Funding/Support: This research was funded by the Swedish Research Council, Swedish program on Chronic inflammation (Combine), and Swedish Foundation for Strategic Research.
Role of the Sponsor: The funders had no role in design and conduct of the study; the collection, management, analysis, and interpretation of the data; or the preparation, review, or approval of the manuscript. The first author had final responsibility for the decision to submit for publication.