Just 1 year ago, in an editorial introducing a theme issue1 on
"Basic Science and Translational Research in JAMA," we stated, "The magnitude,
scope, sophistication, and funding support for biomedical research are unprecedented
and continue to increase dramatically."2 That
statement is even more true today. The National Institutes of Health funding
has doubled during the past decade3; the initial
sequence and analysis of the human genome was published in 20014,5;
and advances in neuroscience, molecular medicine, diagnostic radiology, robotic
surgery, pharmacology, and many other areas herald the application of basic
science to clinical medicine.
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