Author Contributions: Dr Greene had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Greene, Choudhry, Kesselheim, Shrank.
Acquisition of data: Greene, Brennan, Shrank.
Analysis and interpretation of data: Greene, Shrank.
Drafting of the manuscript: Greene.
Critical revision of the manuscript for important intellectual content: Greene, Choudhry, Kesselheim, Brennan, Shrank.
Obtained funding: Shrank.
Administrative, technical, or material support: Brennan, Shrank.
Study supervision: Greene, Shrank.
Conflict of Interest Disclosures: The authors have completed and submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Dr Greene reported receiving a STS Scholars Award by the National Science Foundation, a Junior Faculty Fellowship in Entrepreneurship Research from the Kauffman Foundation, a research grant from CVS Caremark, and royalties from Johns Hopkins University Press for a scholarly monograph entitled Prescribing by Numbers: Drugs and the Definition of Disease. Dr Choudhry reported receiving research grants from CVS Caremark, Aetna, the National Association of Chain Drug Stores, the Robert Wood Johnson Foundation, and the Commonwealth Fund. Dr Kesselheim reported receiving a career development award from the Agency for Healthcare Research and Quality, a Robert Wood Johnson Foundation Investigator Award in Health Policy Research, and serving as an expert witness on behalf of a class of individual plaintiffs against AstraZeneca alleging improper promotion of esomeprazole (Nexium). Dr Shrank reported receiving research grants from CVS Caremark, Aetna, the National Association of Chain Drug Stores, Teva Pharmaceuticals Inc, and Lilly. Dr Brennan reported holding stock or stock options in CVS Caremark.
Funding/Support: This work was supported by a research grant from CVS Caremark.
Role of the Sponsor: Dr Brennan participated in the project but CVS Caremark placed no restrictions on and had no role in the design and conduct of the study; in the collection, analysis, and interpretation of the data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: Mary Kenneally, BA, Elaine Kilabuk, BA, Benjamin Smith, BA, and Kellie Swanton, BA, participated in the primary coding of the advertisements and Jessica Myers, PhD, conducted all statistical analyses. All of the these individuals are associated with the Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital, Boston, Massachusetts, and did not receive compensation for their work.