Immigration of persons to the United States from different parts of the world brings health challenges, including infectious diseases such as tuberculosis, hepatitis B, and Chagas disease. In 2011, the incidence of tuberculosis (new infection or reactivation of latent infection) among persons born outside the United States was 12 times greater than among persons born in the United States.1 The prevalence of hepatitis B infection is at least 10 times higher among those born outside but living in the United States than among those born in the United States.2 An estimated 300 000 persons born in Latin America and living in the United States are infected with Trypanosoma cruzi, the causative parasite of Chagas disease, with less than 10 cases of new infection occurring in the United States since 1955.3
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