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JAMA. 1963;183(8):712. doi:10.1001/jama.1963.03700080120030.
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Diabetes and Cystic Fibrosis.  —During the Bichat colloquia which were held at Paris in October, 1962, H. P. Klotz and L. Israel presented their study of 125 diabetic adults and 152 contratest subjects in whom the authors tried to show an occult cystic fibrosis. The authors found (by a sweat test) positive cases in 20% of the diabetics, a percentage eight times higher than that for the contratest subjects. According to the authors, diabetes is a long-term consequence of cystic fibrosis and the pancreatitis which the fibrosis causes. It is well known that cystic-fibrotic pancreatitis in a child may be fatal. If, then, the heterozygotes reach adult age, there are found more occult pancreatic alterations among them. The alterations progress throughout life, and persons having them are more prone to diabetes than are others. The authors emphasize that it is possible to discover diabetes early in certain persons by means


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