0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
Other Articles |

Biopsy of the Bronchial Wall as an Aid in Diagnosis of Sarcoidosis

Oscar H. Friedman, MD; Stanley M. Blaugrund, MD; Louis E. Siltzbach, MD
JAMA. 1963;183(8):646-650. doi:10.1001/jama.1963.03700080054015.
Text Size: A A A
Published online

Involvement of the bronchial wall in sarcoidosis is more common than previously realized. The distinctive non-caseating, epithelioid-cell granulomas were found on bronchoscopic biopsy in 22 of 35 patients. Symptoms of bronchial obstruction were often absent, and the bronchial mucosa frequently had a normal appearance in spite of microscopic granulomatous involvement. Positive biopsies were obtained on bronchoscopy from 18 of 27 patients with disseminated pulmonary lesions, but even in 4 of 8 patients with bilateral hilar node enlargement alone, random bronchoscopic biopsies disclosed granulomatous seeding. Since bronchial granulomas persist into the late stage of pulmonary sarcoidosis, bronchial biopsy corroborates the diagnosis when other sources such as scalene fat pad and Nickerson-Kveim test sites may prove unrewarding. Random bronchoscopic biopsy adds a new and simple technique for the tissue diagnosis of intrathoracic sarcoidosis.

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Figures

Tables

References

Letters

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();