Editorials |


JAMA. 1964;190(13):1125. doi:10.1001/jama.1964.03070260037013.
Text Size: A A A
Published online

Endarteritis obliterans has been considered an obliterating, proliferative thickening of the intima due either to a diminished functional demand or to irritants diffusing from a chronic inflammatory lesion nearby. Diffusing irritants have been invoked as the prime etiological factor in the pathogenesis of endarteritis obliterans in the vicinity of chronic peptic ulcers, but current textbooks of pathology provide inadequate and conflicting descriptions of these vascular changes.

A description of the histological features of blood vessels near chronic peptic ulcers, and a comparison with vessels at some distance from the ulcer, appears in the December issue of the Archives of Pathology.1 Arterial changes in the vicinity of the ulcers appear to be localized accentuations of either arteriosclerosis or diffuse hyperplastic sclerosis, which normally occur in gastric, intrarenal, and other visceral arteries. Striking similarities to atherosclerosis, diffuse hyperplastic sclerosis (arteriosclerosis), and arteriolosclerosis are noted. The predominant features described are not those


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.