0
We're unable to sign you in at this time. Please try again in a few minutes.
Retry
We were able to sign you in, but your subscription(s) could not be found. Please try again in a few minutes.
Retry
There may be a problem with your account. Please contact the AMA Service Center to resolve this issue.
Contact the AMA Service Center:
Telephone: 1 (800) 262-2350 or 1 (312) 670-7827  *   Email: subscriptions@jamanetwork.com
Error Message ......
MEDICAL NEWS |

Plasmin Therapy Superior for Respiratory Distress Syndrome

JAMA. 1964;190(11):34. doi:10.1001/jama.1964.03070240074038.
Text Size: A A A
Published online

ABSTRACT

In a series of 100 patients with respiratory distress, plasmin therapy with or without additional anticoagulant therapy was found to be superior to classic conservative therapy or anticoagulant therapy alone, Julian L. Ambrus, Roswell Park Memorial Institute, Buffalo, reported in a scientific exhibit at the AMA Clinical Convention.

He also illustrated successful plasmin therapy in patients with hyaline membrane disease.

The question arose whether fibrinolytic enzymes could be prepared from human blood and given in high doses to patients with various thromboembolic diseases in order to achieve therapeutic results.

"Two commercial preparations of plasmin are available at present which use human plasminogen activated with streptokinase," he said. In present studies, urokinase prepared from human urine (possibly an excreted form of human tissue activators) was used to activate human plasminogen isolated from the blood of volunteer donors.

Preliminary studies were performed in experimental animals in which blood clots were induced with

Topics

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

First Page Preview

View Large
First page PDF preview

Figures

Tables

References

CME
Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.

Multimedia

Some tools below are only available to our subscribers or users with an online account.

Sign in

Create a free personal account to sign up for alerts, share articles, and more.

Purchase Options

• Buy this article
• Subscribe to the journal

Related Content

Customize your page view by dragging & repositioning the boxes below.

Jobs
brightcove.createExperiences();