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Letters |

Central Registry for Small-Bowel Ulcers

Arthur C. Allen, MD; Daniel R. Baker, MD; Scott J. Boley, MD; Martin Goldner, MD; Joel F. Panish, MD; R.P. Russell, MD; Wayne H. Schrader, MD; Solomon Schwartz, MD
JAMA. 1964;190(11):1015. doi:10.1001/jama.1964.03070240061024.
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To the Editor:—  In recent years there seems to be a striking increase in the clinical incidence of small-bowel ulceration with attendant stenosis. Lindholmer, Nyman, and Raf in Sweden, and Baker and associates in this country have drawn attention to a possible relationship between this entity and the use of thiazide diuretics in combination with potassium. Because thiazide drugs constitute such and important tool in our therapeutic armamentarium, it is imperative that the available evidence be reviewed and any possible relationships be determined.We are now concerned with a group of more than 80 patients, comprising ( 1) those already reported (see JAMA190:586-590 [Nov 16] 1964) and (2) those to be reported by Morganstern, Freilich, and Panish from Los Angeles, Handel from Detroit, and the group from Brooklyn. While available information is imperfect, the patients from these various centers appear to be similar in a number of ways:


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