Letters |

Safety of Dyclonine

John Adriani, MD
JAMA. 1964;190(1):80. doi:10.1001/jama.1964.03070140086026.
Text Size: A A A
Published online


To the Editor:—  The phrases which Dr. Merifield has quoted out of context certainly create the impression that we regard dyclonine to be free of reactions, but the first two sentences of the same paragraph indicate otherwise. We state that "No ideal drug... is available," and that dyclonine is "relatively safe." The discussion, therefore, adequately conveys our belief that reactions are possible. Our goal was to stress comparative potency and efficacy rather than toxicity. We indicated that the seven or eight most effective drugs are among the more toxic systemically, with the exception of dyclonine, which has a low systemic toxicity.We are familiar with Dr. Merifield's excellent report on his experiences with dyclonine. He found, as we did, that the 1% solution is more effective than the more dilute solutions. We have seen no convulsions with the drug, despite the fact that some staff members utilize the contents of


Sign In to Access Full Content

Don't have Access?

Register and get free email Table of Contents alerts, saved searches, PowerPoint downloads, CME quizzes, and more

Subscribe for full-text access to content from 1998 forward and a host of useful features

Activate your current subscription (AMA members and current subscribers)

Purchase Online Access to this article for 24 hours

First Page Preview

View Large
First page PDF preview




Meets CME requirements for:
Browse CME for all U.S. States
Accreditation Information
The American Medical Association is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The AMA designates this journal-based CME activity for a maximum of 1 AMA PRA Category 1 CreditTM per course. Physicians should claim only the credit commensurate with the extent of their participation in the activity. Physicians who complete the CME course and score at least 80% correct on the quiz are eligible for AMA PRA Category 1 CreditTM.
Note: You must get at least of the answers correct to pass this quiz.
You have not filled in all the answers to complete this quiz
The following questions were not answered:
Sorry, you have unsuccessfully completed this CME quiz with a score of
The following questions were not answered correctly:
Commitment to Change (optional):
Indicate what change(s) you will implement in your practice, if any, based on this CME course.
Your quiz results:
The filled radio buttons indicate your responses. The preferred responses are highlighted
For CME Course: A Proposed Model for Initial Assessment and Management of Acute Heart Failure Syndromes
Indicate what changes(s) you will implement in your practice, if any, based on this CME course.
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Some tools below are only available to our subscribers or users with an online account.

Sign In to Access Full Content

Related Content

Customize your page view by dragging & repositioning the boxes below.