Correctable Renal Hypertension

Albert N. Brest, MD
JAMA. 1964;189(7):590. doi:10.1001/jama.1964.03070070062034.
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The author's stated purpose is to present current information on the etiological theories, the mechanisms, diagnosis, pathology, treatment, and prognosis of renal hypertension. The purpose is fulfilled, although the depth of coverage varies with individual topics.

The chapter on mechanisms tabulates the multiple, often conflicting, experimental data which have accumulated during recent and past years. The postulated roles of angiotensin, pituitary and adrenal influences, alteration in renal artery pulse, baroreceptors, juxtaglomerular apparatus, and other factors are reviewed individually, although the author makes no definite attempt to adjudicate the relative importance of these various factors. Another chapter tabulates the multiplicity of anatomic defects—renal parenchymal, perinephritic, and renovascular —reported as responsible for renal hypertension. The chapter on methods of diagnosing hypertension provides good coverage of the laboratory methods of diagnosis, with particular attention to and a critical review of radioisotope renography. The chapter on surgical and medical treatment of renal hypertension discusses


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