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Multiple Discipline Research Forum |

Diagnostic Procedures of Chronic Amoebiasis

Thomas Doxiades, MD
JAMA. 1964;187(10):719-721. doi:10.1001/jama.1964.03060230047012.
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It IS CONSIDERED that the diagnosis of amoebiasis should be effected through the detection of End-amoeba histolytica in the stools. This method is not at all satisfactory, since a negative stool examination for amoebae does not exclude amoebiasis any more than a negative sputum examination for Bacillus koch excludes tuberculosis of the lungs.1

An ideal solution would be a new serodiagnostic method, since the existing method has not as yet yielded satisfactory results. Failing this, we have tried to find other diagnostic procedures, both in chronic amoebiasis and diffuse nonsuppurative chronic hepatitis.2 Thus all patients who were clinically suspected of suffering from chronic amoebiasis, chronic amoebic hepatitis, or both, were submitted to proctosigmoidoscopic examination with rectal biopsy.

This report, therefore, is based on the observations and conclusions drawn from the application of this method to our patients.

In our department during the year 1962, 695 patients who were


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